Modified protein binders give shortcut to drugs

Published in Chemistry World, 19 Jan 2011

Researchers in Sweden have found a way to boost the specificity of drugs and other protein binders. The method, which involves attaching polypeptides to the binders, could help reduce the work required to develop protein binders into safer drugs.

Almost all drugs are protein binders. They work by interacting with certain proteins so that the proteins’ functions are blocked or stimulated, depending on the effect required. Protein binders are also used in medical diagnostics, industrial protein purification and many other areas of biotechnology and bioanalytical research. […]

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