Published in Chemistry World, 17 Feb 2012
Researchers in the US have created a DNA-based nanorobot that can work its way through cell cultures, delivering cargo only at specific targets. The development could pave the way for programmable therapeutics, in which nanorobots would provide medical treatment only to certain types of cell or tissue.
The field of nanomachines has taken off in recent years, mostly thanks to so-called DNA origami. In this technique, DNA strands can be folded controllably into a structure, onto which different molecules can be attached. Researchers have already shown that structures built using DNA origami can perform basic robotic tasks, such as sensing, computation and targeting cells. But, says biophysicist Shawn Douglas at Harvard Medical School in Boston, Massachusetts, no one has ever combined these tasks to do something more sophisticated, such as cell-targeted cargo delivery. […]
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